Experts Question the Safety of Gardasil

A recent release of documents from the Food and Drug Administration has some medical experts wondering if the vaccination approved to prevent cervical cancer does more harm than good.

Manufactured by Merck, the vaccination called Gardasil has been widely marketed for teenage girls to prevent the onset of human papillomavirus, or HPV, which may lead to cervical cancer. However, FDA records reveal that since the vaccination’s approval in June 2006, it has been associated with 47 deaths, 142 life-threatening incidents, and 6,732 other adverse medical reactions.

Judicial Watch, a government watchdog group, petitioned the FDA to release the documents detailing the problems even as the federal agency considers marketing the vaccination to adult women between the ages of 27 to 45.

A recent study published in the New England Journal of Medicine spells out the problems with the vaccine.

“Despite great expectations and promising results of clinical trials, we still lack sufficient evidence of an effective vaccine against cervical cancer,” said Dr. Charlotte Haug.

She says a number of unanswered questions about the future consequences of the preventative medicine cast doubt on the success of plans for large-scale vaccination programs. The study explains that the clinical trials that gained FDA approval for the vaccine were performed almost exclusively on 11 and 12 year old girls and virtually no long-term studies have been performed in the rush to get the perceived cancer-fighter on the market.

The American College of Pediatrics has joined the New England Journal of Medicine in publicly opposing mandatory vaccination, but that has not stopped lawmakers in 41 states from introducing legislation to require the vaccine or to spend taxpayer dollars educating the public on its perceived benefits.

Some states are even considering mandatory vaccinations for girls entering the sixth grade. Judicial Watch hopes the release of more public information about the documented side effects will get policymakers to think again.

"The FDA adverse event reports on the HPV vaccine read like a catalog of horrors,” said Tom Fitton, president of Judicial Watch. “Any state or local government now beset by Merck’s lobbying campaigns to mandate this HPV vaccine for young girls ought to take a look at these adverse health reports."
Fitton says it may not be appropriate to mandate the vaccine for young girls – or to recommend it for use by adult women.

In her book, The Secret History of the War on Cancer, Dr. Devra Davis also questions the appropriateness of marketing the HPV vaccination to adults.

Davis says early detection in the form of an annual pap smear may be the best defense against cancer. And, even those individuals who have been vaccinated still need to be screened on a regular basis.

According to Dr. Shobha Krishnan of Columbia University, the vaccine is recommended for 11 and 12 year old girls specifically before they become sexually active. She explains this is at the center of the ethical controversy over the vaccination because the viruses that cause the targeted cervical cancers are spread only through sexual contact. Since the vaccine can only help prevent, but cannot cure cancer, Krishnan says that vaccinating older teens and women may not be effective if they are already sexually active.

But, the controversy over HPV vaccinations does not end there.

Despite widespread marketing efforts, the vaccination is still in the testing phase with a final report due in September. It was initially fast-tracked by the FDA, becoming the most expensive vaccination ever to gain federal recommendation, yet the jury is still out on its potential for good or ill.

According to analysis by Judicial Watch, Gardasil is only a preventative or prophylactic inoculation; it cannot cure HPV or treat an infection. Some studies seem to indicate that Gardasil is only effective for a period of two to three years after vaccination. And, while it is meant to prevent cancer by preventing HPV, it is only made for use against four of thirty strains of the disease. Further, the vaccine has not been evaluated for its own ability to cause cancer.

Of the 47 deaths documented by the FDA, all occurred with women under the age of 23, but the largest number of them were much younger ranging in age from 11 to 16. Most of the deaths cite an “unknown” cause of death. Seizures, cardiac arrest, arrhythmia and blood clots were the most commonly named causes. Most often the deaths occurred within 20 days of the inoculation, but some happened within a week.

The FDA tracks the reported instances of Gardasil reactions in a national database called the Vaccination Adverse Effect Reporting System. Even so, Judicial Watch had to file two Freedom of Information requests and a legal complaint before the information was made public.

(from A Woman's View, July 2009)

Monet and Marietta: Degrees of Separation

What do Monet and Marietta have in common?

Visitors to the Columbus Museum of Art this month may be astonished to discover the work of Theodore Earl Butler (1861-1936), who was Claude Monet’s closest apprentice, one of the most renowned American post-Impressionists, and a graduate of Marietta College in the class of 1882.

Butler was born in Columbus, the son of Courtland Philip Livingston Butler (who is President George W. Bush’s paternal great-great-great grandfather!)

After leaving Marietta, he went on to study in New York and then abroad in France. According to gallery owner James Keny of Columbus it was in 1888 that Butler and a fellow Ohioan, Theodore Wendel, boarded a train for Normandy. They disembarked in Giverny where Monet lived and worked his gardens, which were often represented in his paintings. Butler decided to stay and in doing so became one of the first of a colony of artists inspired by Monet that sprung up near Giverny.

It was in this place that Butler married first one and then the other of Monet’s stepdaughters. He married Suzanne in 1892 and after her death married her sister Marthe in 1900. Even though Monet didn’t typically warm to novices, Butler’s marriages seem to have ensured his place at the master’s side. And, he was a family man, often painting scenes from his happy domestic life in works such as Bathing the Child, Suzanne and her Children, and Lily Butler in Claude Monet’s Garden.

The Columbus Museum of Art exhibit available to the public until January 20 features the art of Monet, but supplements it with the work of Butler and others, providing a vivid example of their similarities and differences.

In Ohio, the Columbus Museum of Art, the Keny Galleries in Columbus, the Cincinnati Art Museum and the Cleveland Museum of Art hold several of Butler’s paintings in their permanent collections. His work can also be found at such prestigious locations as: Art Institute of Chicago, Metropolitan Museum of Art, Museé Americain, Giverny, France, and Musée Claude Monet, Giverny, France.



But, there is an example of his finest work to be found even closer to home. In 1915, the artist designed a library bookplate for Marietta College

“The plate shows the seal of the College in the foreground between the two figures representing Wisdom and the Youth who is about to receive the wreath of success. The building in the background represents Erwin Hall, the oldest building on the campus,” said Harry Parker Ward in his book Some American College Bookplates.

Even though the plate has long since been phased out of daily use, it can still be seen inside the front cover of books from the college library archives. Butler himself presented the college with a painting depicting the bookplate scene, but it’s a different work that has found its home with the alumni office. A signed winter scene full of Butler’s favored deep greens and blues has been in storage for many years.

There’s just one note in Butler’s alumni record from Marietta College. After graduation he planned to be a bookkeeper.

Southeastern Ohio's Wine Country

In southeastern Ohio wineries are growing in popularity as the numbers of grape aficionados, as well as the number of producers, are on the rise. The holiday season brings with it an opportunity for a different kind of shopping experience. Far from the retail worlds of catalog and Internet browsing, this trip involves leisurely drives down rustic trails to sip wine from porches that overlook fields of vines.

Shopping for wine in Ohio can be a sensational, social and artistic experience, much like the product itself. The working vineyards and wineries nested in the foothills of Appalachia all have their own unique scenery, personality, and flavor.

Ohio is one of the top ten producing wine states, according to the Ohio Wine Association, making more than 500,000 gallons each year.

Some people feel intimidated at the prospect of wine tasting, fearing that they don’t know enough about it. But, MaryJane Phillips, who owns Marietta Wine Cellars in Marietta along with her husband Allan, says people don’t have to be wine connoisseurs to appreciate a good wine.

“I’m not an expert, I just know what I like,” Phillips said. “Of course, when you visit the winery you get to taste different ones and decide for yourself.”

Marietta Wine Cellars is a boutique winery located in downtown Marietta and specializing in an array of white and red wines, mostly sweet and young, with names like Sternwheeler White and River Red.

It’s a ‘boutique winery’ because they don’t grow their own grapes, just their own brand of hospitality. The wine is made at their location on Front Street where samples are presented in glass tasters. MaryJane says paper or plastic cups just don’t provide the same experience. Guests can stand at the tasting bar or relax in an inviting sit-down tasting room.

Although dry wine is thought of as a traditional, sophisticated favorite, most people prefer sweet wines. Many Appalachian wineries specialize in different varieties. At the Raven’s Glenn Winery near West Lafayette, an award winning dessert wine called Chantilly Lace is the lightest, sweetest wine in the house.

Owner Robert Guilliams says sweet wines account for 80 percent of the wine sales at the Raven’s Glenn and other regional winemakers reported similar results.

The Raven’s Glenn Restaurant pairs Italian dishes with a suggested wine menu in a dining room with a scenic view of the Tuscawaras River and the manicured greens of a golf course beyond. With architecture reminiscent of a resort, it’s not surprising that the idea for the family business grew out of a skiing trip.

“We started to ski when we were about 48 years old. So, we went out to California to ski and went down to Napa and Sonoma and saw all the vines and the wineries down there and started visiting and thought, you know, this might be a neat thing to do as we get ready to look at our own retirement. We were never really thinking it would be something like this. But, the closer we got to doing it, the more we decided this might be good.”

The couple’s goal was a 2,500-gallon winery; at this rate the winery is producing and selling 15,000 gallons of wine a year. Raven’s Glenn serves about 20,000 tasters in their gift shop annually.

Many of these winemakers have several things in common. Many are boomers. For all of these couples, this is a second life, or retirement hobby. For many, it is also a family operation involving siblings, children, and friends who share in the work - and the harvest celebrations.

For Paul and Donna Roberts, owners of the Terra Cotta Vineyards near New Concord, it was a dream they planned for a long time. They searched for the perfect plot of land for more than three years.

“He made wine as a hobby right after we were married, that’s been almost 39 years ago, then we visited wineries for summer vacations,” Donna Roberts said. “We took some classes at Ohio State and then we decided we wanted to do it for retirement.”

The Roberts have two acres of grapes on 52 acres of land with plans to grow to five planted acres.

Like many small wineries, the Roberts rely heavily on word of mouth, and little other advertising, to get the message out about their business. Even so, they host cookouts that sell out every time. As with the others, they maintain a website to post events and accept orders.

The best selling wine at Terra Cotta Vineyards is the Concord Red, a sweet wine, even though the owners prefer their dryer varieties of Seyval, Country Ridge, and Chambourcin.

Since the rolling landscapes of some of the more rustic wineries, like Terra Cotta Vineyards, are located on winding roads off the beaten path it’s a good idea to bring a map and call ahead for hours and directions to insure the best possible shopping experience.

Elkins, W.Va. Develops Railyard Attraction

Developers, entertainers, and investors are setting the stage for the small mountain town of Elkins to become West Virginia's biggest travel destination. At the heart of their focus lies an abandoned train station and rail yard, which is undergoing a thorough transformation.

"We've been trying to make Elkins a destination for years," said Jen Giovannitti, director of the Randolph County Development Authority. "We recognized that we needed a new hotel and to generate more destination activities."

The county authority owns the railroad property and is spearheading the extensive redevelopment project. On the perimeter of the new town square, with the completion of a new Holiday Inn Express (bricked to match the historic motif), the relocation of the Durbin and Greenbrier Valley Railroad, and the start of construction on a new music theatre designed to feature nightly shows, the shared dream is well on its way. A railroad museum is in the works, too. And, all of the new attractions are within walking distance, united by their proximity to the restored depot.

"Still, there is space available in the yards," Giovannitti said.

The former site of a railroad turntable and maintenance shop covers acres of what is rapidly becoming prime visitor space. The comprehensive effort to re-create the space, including the talent, sweat, and funding, is nearly all being invested by residents of Elkins who share a common interest in seeing their hometown thrive.

"We've known about this sort of thing all our lives and we're just so excited to see it come home," said Susie Heckel, manager and producer of the American Mountain Theatre.

Currently in operation in a different location, the American Mountain Theatre is looking forward to the start of construction on the square. The Branson-style variety show will be moving up from a 200-seat makeshift venue to their own custom 525-seat theatre. Now in its second season, the family production has entertained 25 buses this year.

"We'll follow the train season from May to mid-November and then offer a Christmas Spectacular," Heckel said.
Everyone agrees the trains are the main attraction.

"People have a fascination with trains that I don't have an explanation for," said John Smith, president and chief engineer of the Durbin and Greenbrier Valley Railroad. "People will come out of the woodwork to ride."

Smith and his wife Kathy are operating three unique trains on three different scenic excursions around the Cheat Mountain area from Durbin where they also keep a rail and trail store. However, with the availability of nine tracks and a renovated depot at the Elkins town square, the railroad company is looking to relocate and expand.

"It's coming along in Elkins," Smith said. "There's growth potential and it's highly scenic."

Heckel says people from all over the country are already taking the scenic drive through Elkins - mostly on their way to someplace else. Now there are many more reasons to stop.

"One longer term goal is to link Elkins to Snowshoe by train," Giovannitti said. "If that were to eventually come to play it would be a great way to get people into the region."

One travel expert says the reconstruction and centralization of the area's tourism efforts is exactly what the historic railroad town needs to attract and accomodate visitors and realize its potential as a premier d

estination.

"Elkins is the only place in America where visitors can experience a tour with three train rides in a single day," said Bob Cline of US Tours in Parkersburg.

Cline has already been successfully and nearly exclusively selling Elkins' assets and booking dozens of buses annually for the American Mountain Theatre and West Virginia's only scenic railroad. Last year 35,000 people experienced the Durbin and Greenbrier Valley line.

Chaos in Kansas

This is Main Street, Greensburg, Kansas six weeks after an F5 tornado took down everything but the courthouse and grain elevator.

Incredibly and inexplicably some parts of structures remain to identify their previous purpose like this bank depository, the bank vault, and an attached washroom.

This fellow's clothes are still hanging in the closet, but the rest of his home is in ruins.

There's no order or logic to a tornado . . .

Its effects are all so very random.

And strange.

Some folks can find their niche in any storm.

The sign on the door reads: "Space available - see manager for details."


One wall is left of the Boy Scouts meeting lodge.

No walls, but hope remains.